國立成功大學 傳染性疾病及訊息研究中心

Center of Infectious Disease and Signaling Research

2020研究成果發表 共94篇

 

登革病毒研究團隊：

林以行老師(1-6)、彭貴春老師(7-10)、羅玉枝老師(11)、葉才明老師(3, 4, 12)、劉清泉醫師 (2, 6, 13-22)、何宗憲醫師(17, 20, 23-25)、王淑鶯老師(2, 6)、張志鵬老師(4, 5, 26)、余佳益研究員(4, 25)、林秋烽老師(27-29)、簡玉雯醫師(7, 8, 30)、萬書彣老師(4) 。

 

腸病毒研究團隊：

陳舜華老師(24, 31-34)、王貞仁老師(35-38)、劉清泉醫師(2, 6, 13-22)、王世敏醫師(20, 21, 24)、張權發老師(39-41)、徐麗君老師(1, 42-45)、王憲威老師。

 

肝炎病毒研究團隊：

黃溫雅老師(46-52)、張定宗醫師(53-55)、楊孔嘉老師(56)。

 

腸道菌相及細菌致病研究團隊：

蔡佩珍老師(2, 5, 6, 33, 57-59)、吳俊忠老師(2, 6, 60-63)、陳振暐老師(64-66)、鄧景浩老師(60-62, 67-69)、橋本昌征老師 (60, 61, 67-77)、黃一修老師(78)、阮振維老師(79, 80)、吳偉立老師(81-83)。

 

核心平台：

賴明德老師(84-89)、吳尚蓉老師(90-94)。

 

1.    Cheng YY, Chou YT, Lai FJ, Jan MS, Chang TH, Jou IM, et al. Wwox deficiency leads to neurodevelopmental and degenerative neuropathies and glycogen synthase kinase 3β-mediated epileptic seizure activity in mice. Acta Neuropathol Commun. 2020;8(1):6.

2.    Hsieh CL, Hsieh SY, Huang HM, Lu SL, Omori H, Zheng PX, et al. Nicotinamide Increases Intracellular NAD(+) Content to Enhance Autophagy-Mediated Group A Streptococcal Clearance in Endothelial Cells. Front Microbiol. 2020;11:117.

3.    Lee YR, Wu SY, Chen RY, Lin YS, Yeh TM, Liu HS. Regulation of autophagy, glucose uptake, and glycolysis under dengue virus infection. Kaohsiung J Med Sci. 2020;36(11):911-9.

4.    Lu ZY, Cheng MH, Yu CY, Lin YS, Yeh TM, Chen CL, et al. Dengue Nonstructural Protein 1 Maintains Autophagy through Retarding Caspase-Mediated Cleavage of Beclin-1. Int J Mol Sci. 2020;21(24).

5.    Shiau DJ, Kuo WT, Davuluri GVN, Shieh CC, Tsai PJ, Chen CC, et al. Hepatocellular carcinoma-derived high mobility group box 1 triggers M2 macrophage polarization via a TLR2/NOX2/autophagy axis. Sci Rep. 2020;10(1):13582.

6.    Tsai WC, Shen CF, Lin YL, Shen FC, Tsai PJ, Wang SY, et al. Emergence of macrolide-resistant Streptococcus pyogenes emm12 in southern Taiwan from 2000 to 2019. J Microbiol Immunol Infect. 2020.

7.    Chien YW, Wang CC, Wang YP, Lee CY, Perng GC. Risk of Leukemia after Dengue Virus Infection: A Population-Based Cohort Study. Cancer Epidemiol Biomarkers Prev. 2020;29(3):558-64.

8.    Chokephaibulkit K, Chien YW, AbuBakar S, Pattanapanyasat K, Perng GC. Use of Animal Models in Studying Roles of Antibodies and Their Secretion Cells in Dengue Vaccine Development. Viruses. 2020;12(11).

9.    Kuo YT, Liu CH, Li JW, Lin CJ, Jassey A, Wu HN, et al. Identification of the phytobioactive Polygonum cuspidatum as an antiviral source for restricting dengue virus entry. Sci Rep. 2020;10(1):16378.

10.  Wu CC, Yen HY, Lai LT, Perng GC, Lee CR, Wu SJ. A Label-Free Impedimetric Genosensor for the Nucleic Acid Amplification-Free Detection of Extracted RNA of Dengue Virus. Sensors (Basel). 2020;20(13).

11.   Lo YC, Janta P. Resident's Perspective on Developing Community-Based Tourism - A Qualitative Study of Muen Ngoen Kong Community, Chiang Mai, Thailand. Front Psychol. 2020;11:1493.

12.  Lai YC, Chao CH, Yeh TM. Roles of Macrophage Migration Inhibitory Factor in Dengue Pathogenesis: From Pathogenic Factor to Therapeutic Target. Microorganisms. 2020;8(6).

13.  Chen SD, Ju YT, Wei YJ, Hsieh ML, Liu CC, Wu JM, et al. Timing of Endotracheal Intubation in Patients with Fulminant Enterovirus 71 Infection. Medicina (Kaunas). 2020;56(4).

14.  Chen YH, Huang KA, Huang YC, Chi H, Lu CY, Chang LY, et al. Prevalence and molecular characterizations of Staphylococcus aureus nasal colonization among patients in pediatric intensive care units in Taiwan. Antimicrob Resist Infect Control. 2020;9(1):41.

15.  Cheng TY, Liu CC, Jhou DY, Chen CC. Impact of coupling topology upon noise robustness of small optical reservoirs. Sci Rep. 2020;10(1):14086.

16.  Chi H, Huang YC, Liu CC, Chang KY, Huang YC, Lin HC, et al. Characteristics and etiology of hospitalized pediatric community-acquired pneumonia in Taiwan. J Formos Med Assoc. 2020;119(10):1490-9.

17.  Ho TS, Weng TC, Wang JD, Han HC, Cheng HC, Yang CC, et al. Comparing machine learning with case-control models to identify confirmed dengue cases. PLoS Negl Trop Dis. 2020;14(11):e0008843.

18.  Kung YH, Chi H, Liu CC, Huang YC, Huang YC, Wu FT, et al. Hospital-based surveillance of severe rotavirus gastroenteritis and rotavirus strains in young Taiwanese children. J Formos Med Assoc. 2020;119(7):1158-66.

19.  Lee PI, Huang YC, Hwang KP, Liu CC, Chiu CH, Chen PY, et al. Recommendations for the use of Japanese encephalitis vaccines. Pediatr Neonatol. 2020;61(1):3-8.

20.  Lin WT, Liu CC, Wang SM, Ho TS, Yu YT, Chen WC, et al. Actinomyces and Actinobacillus mixed infection with abdominal wall and intrathoracic pseudotumor. Pediatr Neonatol. 2020;61(2):245-7.

21.  Shen CF, Wang SM, Chi H, Huang YC, Huang LM, Huang YC, et al. The potential role of pneumococcal conjugate vaccine in reducing acute respiratory inflammation in community-acquired pneumococcal pneumonia. J Biomed Sci. 2020;27(1):88.

22.  Wu CY, Chi H, Liu CC, Huang YC, Huang YC, Lin HC, et al. Clinical characteristics and risk factors for children with norovirus gastroenteritis in Taiwan. J Microbiol Immunol Infect. 2020.

23.  Chen YP, Ho TS, Lee PC, Chang HH, Shieh GS, Lee CI, et al. Effects of Chinese and Western Medicine on Patients with Dengue Fever. Am J Chin Med. 2020;48(2):329-40.

24.  Shen CF, Ho TS, Wang SM, Liao YT, Hu YS, Tsai HP, et al. The cellular immunophenotype expression of influenza A virus and influenza B virus infection in children. Clin Immunol. 2020;219:108548.

25.  Su CI, Kao YT, Chang CC, Chang Y, Ho TS, Sun HS, et al. DNA-induced 2'3'-cGAMP enhances haplotype-specific human STING cleavage by dengue protease. Proc Natl Acad Sci U S A. 2020;117(27):15947-54.

26.  Chang CP, Hu MH, Hsiao YP, Wang YC. ST2 Signaling in the Tumor Microenvironment. Adv Exp Med Biol. 2020;1240:83-93.

27.  Hsieh TH, Tsai TT, Chen CL, Shen TJ, Jhan MK, Tseng PC, et al. Senescence in Monocytes Facilitates Dengue Virus Infection by Increasing Infectivity. Front Cell Infect Microbiol. 2020;10:375.

28.  Shen TJ, Chen CL, Jhan MK, Tseng PC, Lin CF. CNS Immune Profiling in a Dengue Virus-Infected Immunocompetent Outbred ICR Mice Strain. Front Cell Infect Microbiol. 2020;10:557610.

29.  Tsai CC, Tsai CK, Tseng PC, Lin CF, Chen CL. Glycogen Synthase Kinase-3β Facilitates Cytokine Production in 12-O-Tetradecanoylphorbol-13-Acetate/Ionomycin-Activated Human CD4(+) T Lymphocytes. Cells. 2020;9(6).

30.  Ke TM, Lin LC, Huang CC, Chien YW, Ting WC, Yang CC. High neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio predict poor survival in rectal cancer patients receiving neoadjuvant concurrent chemoradiotherapy. Medicine (Baltimore). 2020;99(17):e19877.

31.  Hsu SM, Yang CH, Teng YT, Tsai HY, Lin CY, Lin CJ, et al. Suppression of the Reactive Oxygen Response Alleviates Experimental Autoimmune Uveitis in Mice. Int J Mol Sci. 2020;21(9).

32.  Hsu SM, Yang CH, Tsai HY, Lin CJ, Fang YH, Shieh CC, et al. Chitosan Oligosaccharides Suppress Nuclear Factor-Kappa B Activation and Ameliorate Experimental Autoimmune Uveoretinitis in Mice. Int J Mol Sci. 2020;21(21).

33.  Leu SY, Kuo LH, Weng WT, Lien IC, Yang CC, Hsieh TT, et al. Loss of EGR-1 uncouples compensatory responses of pancreatic β cells. Theranostics. 2020;10(9):4233-49.

34.  Yao HW, Wang LC, Tsai HY, Fang YH, Zheng C, Chen SH, et al. Bortezomib induces HSV-1 lethality in mice with neutrophil deficiency. J Leukoc Biol. 2020;107(1):105-12.

35.  Huang SW, Tai CH, Hsu YM, Cheng D, Hung SJ, Chai KM, et al. Assessing the application of a pseudovirus system for emerging SARS-CoV-2 and re-emerging avian influenza virus H5 subtypes in vaccine development. Biomed J. 2020;43(4):375-87.

36.  Huang SW, Tsai HP, Hung SJ, Ko WC, Wang JR. Assessing the risk of dengue severity using demographic information and laboratory test results with machine learning. PLoS Negl Trop Dis. 2020;14(12):e0008960.

37.  Hung SJ, Hsu YM, Huang SW, Tsai HP, Lee LYY, Hurt AC, et al. Genetic variations on 31 and 450 residues of influenza A nucleoprotein affect viral replication and translation. J Biomed Sci. 2020;27(1):17.

38.  Tsai HP, Yeh CS, Lin IT, Ko WC, Wang JR. Increasing Cytomegalovirus Detection Rate from Respiratory Tract Specimens by a New Laboratory-Developed Automated Molecular Diagnostic Test. Microorganisms. 2020;8(7).

39.  Chan HC, Ke LY, Lu HT, Weng SF, Chan HC, Law SH, et al. An Increased Plasma Level of ApoCIII-Rich Electronegative High-Density Lipoprotein May Contribute to Cognitive Impairment in Alzheimer's Disease. Biomedicines. 2020;8(12).

40.  Ke LY, Chan HC, Chen CC, Chang CF, Lu PL, Chu CS, et al. Increased APOE glycosylation plays a key role in the atherogenicity of L5 low-density lipoprotein. Faseb j. 2020;34(7):9802-13.

41.  Lin GY, Chang CF, Lan CY. The interaction Between Carbohydrates and the Antimicrobial Peptide P-113Tri is Involved in the Killing of Candida albicans. Microorganisms. 2020;8(2).

42.  Chen SM, Chieng WW, Huang SW, Hsu LJ, Jan MS. The synergistic tumor growth-inhibitory effect of probiotic Lactobacillus on transgenic mouse model of pancreatic cancer treated with gemcitabine. Sci Rep. 2020;10(1):20319.

43.  Chen SM, Hsu LJ, Lee HL, Lin CP, Huang SW, Lai CJ, et al. Lactobacillus Attenuate the Progression of Pancreatic Cancer Promoted by Porphyromonas Gingivalis in K-ras(G12D) Transgenic Mice. Cancers (Basel). 2020;12(12).

44.  Chou YT, Lai FJ, Chang NS, Hsu LJ. Wwox Deficiency Causes Downregulation of Prosurvival ERK Signaling and Abnormal Homeostatic Responses in Mouse Skin. Front Cell Dev Biol. 2020;8:558432.

45.  Huang SS, Hsu LJ, Chang NS. Functional role of WW domain-containing proteins in tumor biology and diseases: Insight into the role in ubiquitin-proteasome system. FASEB Bioadv. 2020;2(4):234-53.

46.  Bao CY, Hung HC, Chen YW, Fan CY, Huang CJ, Huang W. Requirement of cyclin-dependent kinase function for hepatitis B virus cccDNA synthesis as measured by digital PCR. Ann Hepatol. 2020;19(3):280-6.

47.  Ding J, Chen X, Bao K, Yang J, Liu N, Huang W, et al. Assessing different anthropometric indices and their optimal cutoffs for prediction of type 2 diabetes and impaired fasting glucose in Asians: The Jinchang Cohort Study. J Diabetes. 2020;12(5):372-84.

48.  Gong M, Dong H, Tang Y, Huang W, Lu F. Effects of aromatherapy on anxiety: A meta-analysis of randomized controlled trials. J Affect Disord. 2020;274:1028-40.

49.  Huang Y, Chen Z, Wang Y, Han L, Qin K, Huang W, et al. Clinical characteristics of 17 patients with COVID-19 and systemic autoimmune diseases: a retrospective study. Ann Rheum Dis. 2020;79(9):1163-9.

50.  Lin WL, Hung JH, Huang W. Association of the Hepatitis B Virus Large Surface Protein with Viral Infectivity and Endoplasmic Reticulum Stress-mediated Liver Carcinogenesis. Cells. 2020;9(9).

51.  Yang J, Yang A, Cheng N, Huang W, Huang P, Liu N, et al. Sex-specific associations of blood and urinary manganese levels with glucose levels, insulin resistance and kidney function in US adults: National health and nutrition examination survey 2011-2016. Chemosphere. 2020;258:126940.

52.  Zheng H, Huang W, He B, Tan H, Lin P, Zha Z. Positive effects of platelet-rich plasma (PRP) and a Sanguisorba officinalis polysaccharide on the proliferation and differentiation of anterior cruciate ligament (ACL) fibroblasts in vitro. Pharm Biol. 2020;58(1):297-305.

53.  Chang TT, Ho CH. Plasma proteome atlas for differentiating tumor stage and post-surgical prognosis of hepatocellular carcinoma and cholangiocarcinoma. PLoS One. 2020;15(8):e0238251.

54.  Kuo HY, Chiang NJ, Chuang CH, Chen CY, Wu IC, Chang TT, et al. Impact of Immune Checkpoint Inhibitors with or without a Combination of Tyrosine Kinase Inhibitors on Organ-Specific Efficacy and Macrovascular Invasion in Advanced Hepatocellular Carcinoma. Oncol Res Treat. 2020;43(5):211-20.

55.  Liu WC, Wu IC, Chiu YC, Tseng KC, Chen CY, Chiu HC, et al. Genotyping of immune-related loci associated with delayed HBeAg seroconversion in immune-active chronic hepatitis B patients. Antiviral Res. 2020;176:104719.

56.  Tsai P, Lin TY, Cheng SL, Sun HY, Chen SF, Young KC. Differential dynamics of hepatic protein expressions with long-term cultivated hepatitis C virus infection. J Microbiol Immunol Infect. 2020;53(5):715-23.

57.  Chen Y, Huang K, Chen LK, Wu HY, Hsu CY, Tsai YS, et al. Membrane Cholesterol Is Crucial for Clostridium difficile Surface Layer Protein Binding and Triggering Inflammasome Activation. Front Immunol. 2020;11:1675.

58.  Lee JC, Hung YP, Tsai BY, Tsai PJ, Ko WC. Severe Clostridium difficile infections in intensive care units: Diverse clinical presentations. J Microbiol Immunol Infect. 2020.

59.  Yang YJ, Chen PC, Lai FP, Tsai PJ, Sheu BS. Probiotics-Containing Yogurt Ingestion and H. pylori Eradication Can Restore Fecal Faecalibacterium prausnitzii Dysbiosis in H. pylori-Infected Children. Biomedicines. 2020;8(6).

60.  Huang WC, Hashimoto M, Shih YL, Wu CC, Lee MF, Chen YL, et al. Peptidoglycan Endopeptidase Spr of Uropathogenic Escherichia coli Contributes to Kidney Infections and Competitive Fitness During Bladder Colonization. Front Microbiol. 2020;11:586214.

61.  Huang WC, Lin CY, Hashimoto M, Wu JJ, Wang MC, Lin WH, et al. The role of the bacterial protease Prc in the uropathogenesis of extraintestinal pathogenic Escherichia coli. J Biomed Sci. 2020;27(1):14.

62.  Tseng CC, Lin WH, Wu AB, Wang MC, Teng CH, Wu JJ. Escherichia coli FimH adhesins act synergistically with PapGII adhesins for enhancing establishment and maintenance of kidney infection. J Microbiol Immunol Infect. 2020.

63.  Wang MC, Zaydi AI, Lin WH, Lin JS, Liong MT, Wu JJ. Putative Probiotic Strains Isolated from Kefir Improve Gastrointestinal Health Parameters in Adults: a Randomized, Single-Blind, Placebo-Controlled Study. Probiotics Antimicrob Proteins. 2020;12(3):840-50.

64.  Chen JW, Huang HH, Chang SM, Scaria J, Chiu YL, Chen CM, et al. Antibiotic-Resistant Escherichia coli and Sequence Type 131 in Fecal Colonization in Dogs in Taiwan. Microorganisms. 2020;8(9).

65.  Chen YW, Yeh WH, Tang HJ, Chen JW, Shu HY, Su YC, et al. UvrY is required for the full virulence of Aeromonas dhakensis. Virulence. 2020;11(1):502-20.

66.  Tsai CM, Chen JW, Lin WC. Effects of Acanthamoeba castellanii on the dissolved oxygen and the microbial community under the experimental aquatic model. Exp Parasitol. 2020;218:107985.

67.  Hsu PC, Chen CS, Wang S, Hashimoto M, Huang WC, Teng CH. Identification of MltG as a Prc Protease Substrate Whose Dysregulation Contributes to the Conditional Growth Defect of Prc-Deficient Escherichia coli. Front Microbiol. 2020;11:2000.

68.  Huang WC, Liao YJ, Hashimoto M, Chen KF, Chu C, Hsu PC, et al. cjrABC-senB hinders survival of extraintestinal pathogenic E. coli in the bloodstream through triggering complement-mediated killing. J Biomed Sci. 2020;27(1):86.

69.  Matsumoto T, Hashimoto M, Teng CH, Hsu PC, Ota Y, Takamizawa M, et al. Molecular characterization of a carbon dioxide-dependent Escherichia coli small-colony variant isolated from blood cultures. Int J Med Microbiol. 2020;310(5):151431.

70.  Fujita K, Yamamoto Y, Kanai O, Okamura M, Hashimoto M, Nakatani K, et al. Retreatment with anti-PD-1 antibody in non-small cell lung cancer patients previously treated with anti-PD-L1 antibody. Thorac Cancer. 2020;11(1):15-8.

71.  Fujita K, Yamamoto Y, Kanai O, Okamura M, Hashimoto M, Nakatani K, et al. Incidence of Active Tuberculosis in Lung Cancer Patients Receiving Immune Checkpoint Inhibitors. Open Forum Infect Dis. 2020;7(5):ofaa126.

72.  Hashimoto M, Horimoto K, Takeda K, Oshio M, Sawai S, Oshio Y, et al. [The Early Removal of the Implant after Nuss Procedure Due to the Infection in Case of Pectus Excavatum with Atopic Dermatitis]. Kyobu Geka. 2020;73(13):1080-3.

73.  Hirayama J, Hashimoto M, Sakamoto T. Clinical Outcomes Based on Preoperative Kambin's Triangular Working Zone Measurements on 3D CT/MR Fusion Imaging to Determine Optimal Approaches to Transforaminal Endoscopic Lumbar Diskectomy. J Neurol Surg A Cent Eur Neurosurg. 2020;81(4):302-9.

74.  Nagatani Y, Hashimoto M, Oshio Y, Sato S, Hanaoka J, Fukunaga K, et al. Preoperative assessment of localized pleural adhesion: Utility of software-assisted analysis on dynamic-ventilation computed tomography. Eur J Radiol. 2020;133:109347.

75.  Okamura M, Fujita K, Yamamoto Y, Kanai O, Nakatani K, Horimoto K, et al. Single-center analysis of antiresorptive agent-related osteonecrosis of the jaw in lung cancer patients. Asia Pac J Clin Oncol. 2020;16(6):380-4.

76.  Yamaguchi A, Nakayama H, Morita Y, Sakamoto H, Kitamura T, Hashimoto M, et al. Enhanced and Prolonged Activity of Enzymes Adsorbed on TEMPO-Oxidized Cellulose Nanofibers. ACS Omega. 2020;5(30):18826-30.

77.  Sato S, Nagatani Y, Hashimoto M, Nitta N, Hanaoka J, Ushio N, et al. Usability of the lateral decubitus position on four-dimensional ultra-low-dose computed tomography for the detection of localized pleural adhesion in the pulmonary apical region. Acta Radiol. 2021;62(4):462-73.

78.  Kang CY, Huang IH, Chou CC, Wu TY, Chang JC, Hsiao YY, et al. Functional analysis of Clostridium difficile sortase B reveals key residues for catalytic activity and substrate specificity. J Biol Chem. 2020;295(11):3734-45.

79.  Lai CY, Yeh DW, Lu CH, Liu YL, Chuang YC, Ruan JW, et al. Epigenetic Silencing of Ubiquitin Specific Protease 4 by Snail1 Contributes to Macrophage-Dependent Inflammation and Therapeutic Resistance in Lung Cancer. Cancers (Basel). 2020;12(1).

80.  Tsai YT, Ruan JW, Chang CS, Ko ML, Chou HC, Lin CC, et al. Antrodia cinnamomea Confers Obesity Resistance and Restores Intestinal Barrier Integrity in Leptin-deficient Obese Mice. Nutrients. 2020;12(3).

81.  Hu X, Lin JZ, Wu HF, Li JM, Wu WL, Yu HB. [Ectopic seminal tract opening in enlarged prostatic utricle: A report of 22 cases]. Zhonghua Nan Ke Xue. 2020;26(10):911-6.

82.  Wu WL, Lee YC. How Spiritual Leadership Boosts Nurses' Work Engagement: The Mediating Roles of Calling and Psychological Capital. Int J Environ Res Public Health. 2020;17(17).

83.  Wu WL, Lee YC. Do Work Engagement and Transformational Leadership Facilitate Knowledge Sharing? A Perspective of Conservation of Resources Theory. Int J Environ Res Public Health. 2020;17(7).

84.  Cheng LC, Chao YJ, Overman MJ, Wang C, Phan NN, Chen YL, et al. Increased expression of secreted frizzled related protein 1 (SFRP1) predicts ampullary adenocarcinoma recurrence. Sci Rep. 2020;10(1):13255.

85.  Cheng LC, Chao YJ, Wang CY, Phan NN, Chen YL, Wang TW, et al. Cancer-Derived Transforming Growth Factor-β Modulates Tumor-Associated Macrophages in Ampullary Cancer. Onco Targets Ther. 2020;13:7503-16.

86.  Lin YY, Wang CY, Phan NN, Chiao CC, Li CY, Sun Z, et al. PODXL2 maintains cellular stemness and promotes breast cancer development through the Rac1/Akt pathway. Int J Med Sci. 2020;17(11):1639-51.

87.  Liu HL, Yeh IJ, Phan NN, Wu YH, Yen MC, Hung JH, et al. Gene signatures of SARS-CoV/SARS-CoV-2-infected ferret lungs in short- and long-term models. Infect Genet Evol. 2020;85:104438.

88.  Phan NN, Liu S, Wang CY, Hsu HP, Lai MD, Li CY, et al. Overexpressed gene signature of EPH receptor A/B family in cancer patients-comprehensive analyses from the public high-throughput database. Int J Clin Exp Pathol. 2020;13(5):1220-42.

89.  Wang CY, Chiao CC, Phan NN, Li CY, Sun ZD, Jiang JZ, et al. Gene signatures and potential therapeutic targets of amino acid metabolism in estrogen receptor-positive breast cancer. Am J Cancer Res. 2020;10(1):95-113.

90.  Debele TA, Wu HC, Wu SR, Shan YS, Su WP. Combination Delivery of Alpha-Tocopheryl Succinate and Curcumin Using a GSH-Sensitive Micelle (PAH-SS-PLGA) to Treat Pancreatic Cancer. Pharmaceutics. 2020;12(8).

91.  Li WN, Hsiao KY, Wang CA, Chang N, Hsu PL, Sun CH, et al. Extracellular vesicle-associated VEGF-C promotes lymphangiogenesis and immune cells infiltration in endometriosis. Proc Natl Acad Sci U S A. 2020;117(41):25859-68.

92.  Lin CY, Lin YC, Huang CY, Wu SR, Chen CM, Liu HL. Ultrasound-responsive neurotrophic factor-loaded microbubble- liposome complex: Preclinical investigation for Parkinson's disease treatment. J Control Release. 2020;321:519-28.

93.  Shen YR, Wang HY, Tsai YC, Kuo YC, Wu SR, Wang CY, et al. The SEPT12 complex is required for the establishment of a functional sperm head-tail junction. Mol Hum Reprod. 2020;26(6):402-12.

94.  Wang CA, Chang IH, Hou PC, Tai YJ, Li WN, Hsu PL, et al. DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination. J Extracell Vesicles. 2020;9(1):1746529.